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have a digenetic existence cycle, involving a motile, extracellular promastigote stage that parasitizes the alimentary tract of a sandfly vector and an immotile amastigote stage that survives and replicates within the phagolysosomes of mononuclear phagocytes [two,three]. Apart from humans, Major hosts of LeishmaniaIt is necessary to note that root

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The TGF-β signaling pathway is involved with the regulation of progress and proliferation of cells in conjunction with migration, differentiation and apoptosis. See PathwayQuite a few preclinical shreds of evidence display that flavonoids can boost mobile senescence by modulating numerous ageing-associated signalling pathways and cellular protecti

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